The Port of Jackson is located on the Tombigbee Waterway. It is perfect for barge loading and off loading sand gravel and timber.
From Coffeeville Lake to Jackson, Alabama, the Tombigbee River is free flowing. Below Jackson, the Tombigbee River joins the Alabama River on the Mobile-Baldwin county line to form the Mobile River, approximately 30 mi (48 km) north of Mobile.
Before the Tombigbee River was dammed, dredged and straightened as part of the Tennessee-Tombigbee Waterway, a total of fifty freshwater mussel species occurred there, including three species known from nowhere else. But, straightening and dredging caused banks to destabilize and fill the channel with silt and dams created reservoirs where shoals once were. Change of the river from a meandering, free-flowing system with a sand and gravel bottom to this series of reservoirs and channels decimated the mussel community in the Tennessee-Tombigbee Waterway. Few reaches of the river hold significant mussel populations today, and the three species that occurred only in the Tombigbee River are believed to be extinct. But in the few areas where mussels remain, densities can be high. Some mussels in the Tombigbee River are commercially valuable, though the Tombigbee River generally contributes an insignificant portion of the annual commercial harvest.